In Vivo Biology Scientist

Position Details

  • Job Title: In Vivo Biology Scientist
  • Location: New York
  • Job Category: Drug Discovery-Biology

JOB SUMMARY

We seek a highly creative, self-motivated scientist with significant experience in in vivo biology to work as a member of an integrated team developing a novel platform for the discovery of new drug targets and transformational therapeutics.  Reporting to the VP – Drug Discovery Biology, the In Vivo Biology Scientist will be a key member of the group charged with developing, qualifying, and executing in vivo assays to support target validation and drug discovery programs.  Candidates must have broad experience in general phenotyping as well as extensive experience in applicable in vivo pharmacology procedures. Successful candidates must be able to work effectively both in a collaborative setting and independently and possess outstanding written and oral communications skills. 

KEY RESPONSIBILITIES

  • Development, validation and characterization of multiple rodent assays based on disease area prioritization
  • Design and execution of in vivo rodent pharmacokinetic/pharmacodynamic (PK/PD) studies including formulation of dosing solutions, dosing, PK/PD sampling and necropsy
  • Assessment of contract research organization (CRO) capabilities and designing/monitoring/interpreting assays run at CROs
  • Contributions to target validation and drug discovery program strategy by representing in vivo pharmacology on core teams
  • Compilation of results into comprehensive reports

QUALIFICATIONS AND EDUCATION REQUIREMENTS

You must have:

  • PhD degree in a biological science
  • At least five years of hands on research experience with rodent models and pharmacology
  • Demonstrated expertise in in vivo study design and execution
  • Commitment to detail for in vivo study design and data organization
  • Ability to coordinate in vivo experiments conducted by external CROs

Additional preferred experience includes:

  • Drug discovery experience including serving on drug discovery core teams
  • Working with genetically modified animals, including behavioral phenotyping of rodents after optogenetic and/or chemogenetic manipulation

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